The affected fetus carried a causative compound heterozygous mutation c.919‑2 A>G (IVS7‑2 A>G) and c.1707+5 G>A (IVS15+5 G>A) of the solute carrier family 26 member 4 gene inherited from maternal and paternal sides, respectively. In one case, a couple had a 7‑year‑old daughter affected by non‑syndromic sensorineural hearing loss. Termination of the fetus may be considered as an extreme outcome to the discovery of a potential deaf fetus, and therefore preimplantation genetic diagnosis has become an important option for avoiding the birth of affected children without facing the risk of abortion following prenatal diagnosis. Given the high incidence of hearing loss among newborns and the huge cost of treatment and care (including cochlear implantation), prenatal diagnosis is strongly recommended. Hearing loss may place a heavy burden on the patient and patient's family.
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